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An Atlas of Pseudomonas genes
Certain proteins play a crucial role in the processing of genetic information by bacteria: The so-called sigma factors are responsible for the start of transcription, i.e. the process of making RNA from DNA. Recently, Scientists of the Helmholtz Centre for Infection…
Protein renders Yersiniae harmless
Bacteria of the Yersinia genus cause thousands of cases of diarrhoeal disease each year, often with serious consequences. To survive and proliferate in the host, the pathogens first have to adapt, though. Scientists at the Helmholtz Centre for Infection Research (HZI)…
New professorship at the Centre for Structural Systems Biology
How do bacterial pathogens gain entry into our cells and how do they make us ill? Those are the questions that will be investigated by the biochemist Michael Kolbe at the Centre for Structural Systems Biology (CSSB) in Hamburg starting from February 2015. He and his…
An enzyme tunnel in 3D
At high resolution and in 3D - Scientists from the Helmholtz Centre for Infection Research (HZI) and the University of Basel solved the structure of the enzyme, EgtB. Some bacteria utilise EgtB to produce the vitamin ergothioneine, for example Mycobacterium tuberculosis…
Influenza vaccine less effective than expected
The effectiveness of this season's influenza vaccine appears to be less than optimal. The vaccine must be expected to be less effective against one of the three circulating types of the virus, as reported by the Robert Koch-Institute (RKI). Prof Klaus Schughart, head of…
Ineffective Helper Cells
The IKBNS protein is very important for the development of immune cells: Two years ago, it was discovered that regulatory T cells, so-called Tregs, do not develop in the absence of this protein. The IKBNS protein also plays a role in the development of another type of…
Recognising blood poisoning more easily
Every year, more than 150,000 people in Germany become afflicted by Sepsis , also called blood poisoning in the vernacular. The disease is fatal for almost one in three patients. Scientists of the Helmholtz Centre for Infection Research (HZI) in Braunschweig recently…
Emmanuelle Charpentier receives Ernst Jung Award for Medicine
This year’s Ernst Jung Award, worth 300,000 Euro, goes to Prof Emmanuelle Charpentier from the Helmholtz Centre for Infection Research (HZI) in Braunschweig. She receives the prize for harnessing an ancient immune defense in bacteria – CRISPR-Cas9 – into a genome…
Living within the bones
Osteomyelitis is an infection of the bone that is generally associated with high levels of bone marrow inflammation and bone destruction. Scientists of the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, reported how the pathogen Staphylococcus…
The HZI and the University of Würzburg get new institute for infection research off the ground
The Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Julius-Maximilians-Universität Würzburg (JMU) are going to jointly establish a new Helmholtz institute headquartered in Würzburg. This has been decided in a resolution of the Senate of the…