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Interaction Between Immune System and Brain
In an earlier study, the researchers from Braunschweig already showed that the reaction of the immune system during an illness with an influenza virus can have a long-term negative effect on the brain. “We know that in the case of illness there are signalling systems…
Adding flexibility to CRISPR targets in the genome
“The presence of a suitable PAM remains a barrier for directed gene editing,” says Prof Chase Beisel, head of the HIRI research group “RNA Synthetic Biology”. This has led researchers to mine the existing diversity of Cas nucleases in bacteria and archaea for ones that…
Prime Minister of Lower Saxony Stephan Weil and Minister Björn Thümler visit the Helmholtz Centre for Infection Research
At the start of the visit, which began in the HZI Forum conference hall, Prof Dirk Heinz, Scientific Director of the HZI, gave an overview of the HZI’s research strategy and the close collaboration with partners in Lower Saxony: “The aim of our research is to decipher…
Presentation of the SonderMTZ®-Award 2021
Systems Biology as basic research is considered an important starting point for a medicine that increasingly relies on individually targeted disease control. The research objective of the award winner Sahamoddin Khailaie is to understand diseases related to the immune…
Lipid-lowering drugs not a risk factor in COVID-19
Statins are prescribed to lower cholesterol levels. High blood lipid levels are often associated with diseases of the cardiovascular system. Patients taking these drugs therefore belong to the particularly vulnerable risk group for severe courses of COVID-19 infection.…
Key Virulence Factor of Salmonella characterized
The flagella, which is comprised of tens of thousands of flagellin proteins, is not only important for the movement of Salmonella but also plays a key role in its ability to invade the human host cell. The parts of the flagellin proteins that are exposed are highly…
COVID-19-related respiratory failure: Why patients require prolonged ventilation
The majority of patients with severe COVID-19 develop unusually pronounced scarring of the lungs. This was the conclusion of a study conducted by researchers from Charité – Universitätsmedizin Berlin , the Helmholtz Institute for RNA-based Infection Research (HIRI) ,…
Who benefits from immunotherapy against hepatitis B?
It is estimated that more than 250 million people worldwide are chronically infected with the hepatitis B virus. Cytotoxic T cells and T helper cells play an important role in fighting viral infections. The constant activation of these immune cells in chronically…
Joint symposium of HZI and McGill University on personalised infection medicine
Personalised infection medicine aims to take into account individual differences in the diagnosis and therapy of infectious diseases. The HZI and McGill University have been building a strategic cooperation on this topic for several years. Clinicians and scientists from…
20 research, medical and pharmaceutical organizations call on G7 to step up action against antibiotic resistance
They emphasise that it is important to ensure that more incentives are provided for research and development on new anti-bacterial drugs, that new antibiotics against problem germs reach patients quickly, that the potential of vaccines to reduce the risk of bacterial…
