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How multi-resistant pathogens can be defeated
The steadily increasing resistance of many pathogens to antibiotics is one of the major challenges of modern medicine. Many of the common antibiotics have already lost their effect. Accordingly, there is an urgent need for alternatives to antibiotics for the treatment…
Bacterial profiles at the click of a button
Modern sequencing technologies allow deciphering the entire genetic material – the genome – of a bacterium requiring only a short amount of time. This produces a huge amount of data with thousands of genes. However, the analysis of the bacterial properties encoded by…
How gut bacteria can make us ill
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these bacteria. Scientists of the Helmholtz Centre for Infection Research (HZI) in Braunschweig recently were the…
Hospital germs have their flaws too
The pathogen Pseudomonas aeruginosa (P. aeruginosa) uses a variety of tricks to perfectly adapt to its environment. Pseudomonas bacteria can colonise and proliferate in virtually any environment, including the lungs, eyes, urinary tract, an open wound or an implant.…
New therapeutic approaches for necrotising fasciitis
Streptococcus pyogenes is a very wide-spread Streptococcus species known to be the pathogen eliciting bacterial angina, which is also known as tonsillitis. Scarlet fever and middle ear infections can also be caused by this bacterium. Pathogens of the species…
Herrenhausen Symposium on Individualized Infection Medicine
New and recurrent infectious diseases, combined with steadily increasing resistance to antibiotics and the global mobility of people, create enormous new challenges for modern medicine. Consequently, therapies must combine maximum efficacy with minimum toxicity.…
Federal Minister of Research Anja Karliczek and State Minister Björn Thümler visit Infection Research Centres in Hannover
Federal Minister of Research Anja Karliczek and State Minister Björn Thümler today caught up with the current challenges and innovative approaches in modern infection research in Lower Saxony. They visited the HZI-operated study centre of the NAKO health study in…
Empowering scientists to make a difference in translational medicine
One highlight of the course was the lecture from Rodger Novak, the co-founder and president of CRISPR Therapeutics who shared the story of the development of the company CRISPR Therapeutics and stressed the importance of credibility for start-ups. As most participants…
Machine learning flags emerging pathogens
As the cost of genomic sequencing falls, scientists around the world are using genetics to better understand the bacteria causing infections, how diseases spread, how bacteria gain resistance to drugs, and which strains of bacteria may cause outbreaks. However, current…
Inhoffen Medal 2018 awarded to pharmacist Rolf Müller
The Inhoffen Medal, which is awarded by the sponsors' association Friends of the HZI, is considered to be one of the most prestigious awards in the field of natural product chemistry and is endowed with €5000. The award is presented in the scope of the Inhoffen Lecture,…
