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Improved analysis of metagenome data
To study bacteria from a specific habitat, one used to have to culture them in the laboratory. The cultures grown in the laboratory were then analysed and identified. The progress of molecular genetic methods has led to the development of metagenomic methods, which…
Silke Tannapfel is the new administrative director of the HZI
"We at the HZI are extending a warm welcome to Silke Tannapfel as we are looking forward to a good and successful collaboration.“ Dirk Heinz, Scientific Director of the HZI Raised in Nienburg/Weser, Silke Tannapfel studied law at the University of Göttingen and Science…
Silencing bacteria
In a way, bacteria do talk to each other. They do not communicate by words, but rather by chemical signals. This allows them, for example, to coordinate the penetration into a host or their proliferation. This special type of communication is called "quorum sensing".…
Progress against chronic infections
“We have high hopes for this drug candidate,” explained Dr Martin Empting, who is conducting the project at the HIPS/HZI together with Prof Rolf Hartmann and Dr Thomas Hesterkamp. Unlike antibiotics, the substance does not kill the bacterium, it disrupts its ability to…
Easier decoding of unknown protein complexes
Like tiny machines, proteins in our body do hard work. Virtually all processes are performed or controlled by these highly specialised protein molecules. They transmit signals, convert energy, initiate chemical reactions or provide growth and movement. These partially…
European support for rapidly advancing vaccine development
Vaccines are one of the most successful and cost-effective public health tools for disease prevention. Their development though is time-consuming and complex, requiring a combination of specialised skills and technical capacities not readily available at a single…
Virus infections of bone marrow donors influence the outcome of transplantations
In brief: The health of the donor is just as important as that of the recipient for the success of a bone marrow transplantation. „However, our study does not focus on the impeccable health of the donor at the time of the bone marrow donation – since this is a…
Gut microbiota – Tiny helpers against Salmonella
Trillions of microorganisms colonise the surfaces of the human body as permanent, helpful companions. The composition of the so-called microbiota, i.e. the entirety of microorganisms colonising humans and animals, varies very strongly between individuals. Aside from…
Intestinal bacteria affecting the cardiovascular system
Intestinal bacteria are an important component of digestion as they convert food items into substances that can be absorbed by the body. But sometimes, the activity of these bacteria may be harmful to the human body. Certain bacterial degradation products promote the…
Novel agent inhibits communication between bacteria and renders them harmless
Antibiotic-resistant bacteria are on the advance throughout the world. This makes it even more important to develop medications to control these microorganisms. Scientists at Saar-University and at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)…