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Bacteria persist as stowaways
The most widely known Yersinia germ is Yersinia pestis, the cause of the plague that can be transmitted by fleabites. Other species, such as Yersinia enterocolitica and Yersinia pseudotuberculosis, usually enter the human body via contaminated foods, for example raw…
Diversity of "good" intestinal bacteria keeps us healthy
Dietary fibres from our food are decomposed by the local bacterial community in the large intestine to produce short-chain fatty acids, as well as other substances. This provides an energy source to the human body that it would not be able to utilise with just its own…
Petra Dersch admitted to European Academy of Microbiology
"For me, being admitted to the academy is a great honor," says Petra Dersch. "The academy gives me the opportunity to improve my networking with leading microbiologists in Europe, to initiate new common ways to elucidate complex microbiological and infection-biological…
Predicting slippery spots for the ribosome
PRF causes the ribosome to "slip" during translation and change the reading frame to produce a different protein. PRF is used, for example, by viruses that have to produce different proteins with a very limited number of mRNAs in order to multiply. “PRF is not a random…
Large repertoire of new gene editors
Based on the involved proteins, bacterial CRISPR-Cas systems can be divided into two classes. Class II CRISPR systems require only a single protein for targeted DNA editing. In class I, on the other hand, several proteins must interact in a complex called Cascade. Due…
From cancer medication to antibiotic
Antibiotic resistance occurs naturally in bacteria as a mechanism to defend themselves and survive in the course of evolution. However, due to the large-scale and often erroneous use of antibiotic drugs, antibiotic resistant pathogens are becoming more widespread.…
Working together in the fight against tuberculosis and malaria
Tuberculosis and malaria, along with AIDS, are the three major infectious diseases. Tuberculosis is one of the ten most common causes of death worldwide; in 2017 alone, ten million contracted the disease and 1.6 million died. Only increased efforts will make it possible…
Pharmaceutical Research Alliance Saarland launched
The signing of this agreement starts a pilot research alliance between the two major research organisations, the Helmholtz Association and the Leibniz Association, and Saarland University. The aim of the new alliance is to pool the interests of the partner organisations…
Auszeichnung für Wirkstoffforscher Rolf Müller
Die Verleihung der Ehrendoktorwürde an Müller erfolgte anlässlich der erfolgreichen und langjährigen Kooperation zwischen seiner Arbeitsgruppe und der Shandong Universität, zuletzt gefördert im Rahmen des Programmes „Helmholtz International Lab“. Dieses mehrjährige…
Helmholtz gets three more start-ups off the ground
“Scientists at Helmholtz research many questions that are important to the well of our society. But in order to take their results to market respectively in an application, some start-up assistance is helpful,” says Otmar D. Wiestler, President of the Helmholtz…