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CORESMA provides evidence-based data on measures against coronavirus
The healthcare systems of many countries are not prepared for an outbreak of the coronavirus SARS-CoV-2. The Helmholtz Centre for Infection Research (HZI) in Braunschweig coordinates an international project to collect clinical, epidemiological and immunological data in…
With antibody tests and new active substances against SARS-CoV-2
Federal Minister of Education and Research Karliczek explains: “Research is the key to fighting the coronavirus. One can see that this is true in many different ways when looking at the various studies that have been recently launched at the HZI in Braunschweig with…
Small Protein, Big Impact
"We were surprised that a comparatively small protein can have such a great influence on bacterial gene regulation," says Christoph Schoen, professor at the Institute of Hygiene and Microbiology at Julius-Maximilians-Universität ( JMU ) Würzburg in Bavaria, Germany.…
Interaction Between Immune System and Brain
In an earlier study, the researchers from Braunschweig already showed that the reaction of the immune system during an illness with an influenza virus can have a long-term negative effect on the brain. “We know that in the case of illness there are signalling systems…
Adding flexibility to CRISPR targets in the genome
“The presence of a suitable PAM remains a barrier for directed gene editing,” says Prof Chase Beisel, head of the HIRI research group “RNA Synthetic Biology”. This has led researchers to mine the existing diversity of Cas nucleases in bacteria and archaea for ones that…
Prime Minister of Lower Saxony Stephan Weil and Minister Björn Thümler visit the Helmholtz Centre for Infection Research
At the start of the visit, which began in the HZI Forum conference hall, Prof Dirk Heinz, Scientific Director of the HZI, gave an overview of the HZI’s research strategy and the close collaboration with partners in Lower Saxony: “The aim of our research is to decipher…
Presentation of the SonderMTZ®-Award 2021
Systems Biology as basic research is considered an important starting point for a medicine that increasingly relies on individually targeted disease control. The research objective of the award winner Sahamoddin Khailaie is to understand diseases related to the immune…
Lipid-lowering drugs not a risk factor in COVID-19
Statins are prescribed to lower cholesterol levels. High blood lipid levels are often associated with diseases of the cardiovascular system. Patients taking these drugs therefore belong to the particularly vulnerable risk group for severe courses of COVID-19 infection.…
Key Virulence Factor of Salmonella characterized
The flagella, which is comprised of tens of thousands of flagellin proteins, is not only important for the movement of Salmonella but also plays a key role in its ability to invade the human host cell. The parts of the flagellin proteins that are exposed are highly…
COVID-19-related respiratory failure: Why patients require prolonged ventilation
The majority of patients with severe COVID-19 develop unusually pronounced scarring of the lungs. This was the conclusion of a study conducted by researchers from Charité – Universitätsmedizin Berlin , the Helmholtz Institute for RNA-based Infection Research (HIRI) ,…