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Shining a new light on the tug-of-war between virus and host
When RNA viruses, including the coronavirus SARS-CoV-2, infect our cells, they utilize regulatory RNA elements to recruit proteins of virus and host in order to execute their own gene expression program and enable the production of viral progeny. Understanding the…
What defines a human and healthy microbiome?
Scientists from the Collaborative Research Center 1182 "Origin and Function of Metaorganisms" in Kiel and the Helmholtz Institute for One Health (HIOH) have now compared microbiome data from various great apes with those of humans with rural and urban lifestyles in the…
Paths into the unknown
EM started in 1982 at the former Gesellschaft für Biotechnologische Forschung (GBF) and in 1989 moved into a new building, which presented a major challenge in itself: The floors of the new building were covered with vibrating screed, which is not suitable for…
How we protect ourselves from infections
Viruses, bacteria, fungi and yeasts are lurking everywhere. Whether at home or work, in the hospital or even on or in human bodies – they can be found on every centimetre of every surface on Earth. The vast majority of microorganisms and viruses, which are not counted…
“Sample das Saarland” – microbial treasures from soil
The increasing resistance of pathogens to known antibiotics is an alarming trend that has gained public awareness over the last couple of years, as more and more infections with multi-resistant germs are reported from the clinics where even treatment with reserve…
Racing against pathogens
Prof Rolf Müller, who is the speaker of the research topic “Anti-infectives” at the Helmholtz Centre for Infection Research (HZI) and the Executive Director of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) in Saarbrücken, summarises the status quo…
From the computer to the pharmacy
In the UdS focus area NanoBioMed, the nextAID³ cluster is planning new and innovative approaches for AI-driven drug research and development. In order to successfully combine experimental and computer-aided research, an interdisciplinary team of over 40 researchers has…
Alliance of Science Organisations condemns anti-democratic endeavours
The many protests throughout Germany are an impressive demonstration of the deep solidarity in our society. We regard the clear commitment of the many people who are visibly standing up for the fundamental values of our democracy at this time as an enormously…
New findings on Bacteroides thetaiotaomicron physiology under bile stress
Bacteroides thetaiotaomicron is an abundant member of the human intestinal microbiota. The bacterium supports the digestion of polysaccharides and is of paramount importance for human health, but it can also cause or promote infections. As a model organism, B.…
HZI Molecule Transformed into a Cancer Medicine in the United States
The pharmaceutical company Bristol-Myers Squibb (BMS) recently obtained approval in the American market for IXEMPRA, a semi-synthetic analog of epothilone B, for the treatment of patients with metastatic breast cancer resistant or refractory to anthracyclines, taxanes,…
