Search
Displaying results 121 to 130 of 231.
Prof Dr Alice McHardy
Prof Dr Alice McHardy Head of Research Group +49 531 391-55271 E-Mail Alice Carolyn McHardy holds a diploma in biochemistry and a doctoral degree (Dr. rer. nat) in bioinformatics, both from Bielefeld University in Germany. From 2005 to 2007 she first was a…
Prof. Dr. Till Strowig
Prof Dr Till Strowig Head of Research Group +49 531 6181-4700 E-Mail Till Strowig studied Medical Biotechnology at the “Technische Universität” Berlin. After his diploma thesis at The Rockefeller University in New York, he remained there for his Ph.D.…
Prof. Dr. Wulf Blankenfeldt
Prof Dr Wulf Blankenfeldt Head of Department +49 531 6181-7000 E-Mail Wulf Blankenfeldt studied chemistry at the Technische Universität Braunschweig (TU) and earned his doctorate in “Crystal structure analysis of tyrosine aminotransferase from Trypanosoma…
Prof. Dr. Dr. h.c. Dirk Heinz
Prof Dr Dr h.c. Dirk Heinz Head of Department +49 531 6181-3700 E-Mail Dirk Heinz is a German biochemist and structural biologist. He studied chemistry in Freiburg/Germany and received his PhD in structural biology from the University of Basel/Switzerland.…
Prof. Dr. Luka Cicin-Sain
Prof Dr Dr Luka Cicin-Sain Head of Research Group +49 531 6181-4608 E-Mail Born in Croatia, Luka Cicin-Sain studied medicine at the University of Rijeka, his hometown. In 1996, he received his M.D. After that he studied biomedicine and spent a year as a…
Single-cell Analysis
Pathogenic bacteria can reside in a mammalian host for a life-long period and chronic carriers form a reservoir leading to recurrent infections. Despite the importance of chronic infections for public health, how a subset of pathogens escape the host’s immune surveillance and how the host contains the spread of bacteria are still poorly understood. Scientists within the Single-Cell Analysis group develop and use single-cell transcriptomics and computational approaches to decipher the microenvironments of individual pathogens and ultimately their functional consequences on infection outcome. This group is located at the Helmholtz Institute for RNA-based Infection Research (HIRI).
Chemical Biology
In their ongoing quest for new therapies against pathogens, scientists are focusing primarily on chemical agents. Discovering new bioactive compounds, characterising their functionality and optimising their properties are the three main goals of the Department of Chemical Biology (CBIO) at the HZI.
Biological Barriers and Drug Delivery
While considering the confusing flood of drugs in the pharmacies it is hard to believe in a lack of medication. But there are still many infectious diseases and also cancer that cannot be treated sufficiently. During a medical treatment it is essential that the drug arrives at the envisaged body region. Read more about the research of the department “Biological Barriers and Drug Delivery” on techniques for the correct distribution of novel drugs. This group is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) .
Anti-infectives from Microbiota
The department of Prof Christine Beemelmanns focuses on the identification and functional analysis of novel anti-infective natural products from microbial communities. Co-cultivation studies as well as cell-based assays in combination with chemical-analytical and molecular-biological methods are used to evaluate and prioritize novel natural product producers. The department uses established and innovative metabolomic-, activity and genome-based methods to identify and determine the structure of the secreted natural products. Based on the isolated novel natural substances, the functional analysis and evaluation of their range of effects is carried out. This department is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) .
