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Displaying results 61 to 70 of 83.
Viral Immunology
“Back then, I wasn’t ill so often”: With advancing age not only the skin loses its elasticity – many organs lose their functions. So does the immune system: Defense cells do not react promptly anymore, and immunological memory is not established. As a result, we are poorly protected by vaccines and more susceptible to infections, but at the same time suffer from inflammatory disease. While the mechanisms of immune aging remain unknown, chronic viral infections are environmental factors that may accelerate the age-related changes of the immune system. Read more about how pathogens may have an impact on the real age of our immune system.
Drug Design and Optimization
In order to combat the increasing number of resistant pathogens, the development of new anti-infective drugs is an important goal for pharmaceutical research. Efficient medications with novel modes-of-action to fight infectious diseases are urgently needed. Below, you may read more about the design, identification and optimisation of new drug candidates. This group is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) .
Drug Bioinformatics
Bioinformatics is instrumental in all areas of molecular biology, from analysis of genome sequences towards predicting three-dimensional structure of drug-target complexes. We apply cutting-edge bioinformatics and computer science techniques for discovery of novel resistance mechanisms and predicting mode-of-action of bioactive compounds. This group is located at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)
Central Facility for Microscopy
Light microscopy and electron microscopy are excellent high resolution tools to investigate the adhesion and invasion mechanisms of pathogenic bacteria. High resolution electron microscopy permits to examine and unravel pathogenicity mechanisms on a morphological basis. ZEIM offers equipment and highly sophisticated expertise for the preparation and observation of biological samples.
Cellular Proteome Research
Pathogenic bacteria and viruses utilize and manipulate cellular processes of our immune system. The identification of protein functions in the human immune system that decisively control the progression of infections constitutes the central aim of the research group Cellular Proteomics at the HZI.
Postdoc with focus on translational activities: clinical development of a method to assess cancer risk and immune defects (m/w/d)
The PERI department, headed by Prof Dr Kathrin de la Rosa, is offering a postdoctoral position.
Postdoc that combines science and management: B cells and antibodies for novel solutions in infectious diseases (m/w/d)
The PERI department, headed by Prof Dr Kathrin de la Rosa, is offering a postdoctoral position.
Head (f/m/d) of the ‘Corporate Controlling’ team
The ‘Finance and Controlling’ department is looking for a manager for the ‘Corporate Controlling’ team
Employee / Research Officer - EU/national/international (f/m/d)
The department External Funding Acquisition is looking for a Research Officer to start as soon as possible.
Masterstudent (m/f/d)
The Helmholtz Centre for Infection Research (HZI), Department of Respiratory Infection Dynamics (DINF), led by Prof. Dr. med. Hortense Slevogt, is seeking a master's student to join the team at the earliest opportunity.